谢小敏副研究员

办公电话:021-54748925
电子邮件:xiaominxie@sjtu.edu.cn
通讯地址:上海市东川路800号中国赌博十大网站B楼526室

  • 教育背景

    1994-1998:黑龙江大学中国赌博十大网站,学士
    1998-2001:黑龙江大学中国赌博十大网站,硕士
    2001-2004:华东理工大学化学与分子工程学院,博士

    2014-2015: 美国威斯康辛大学麦迪逊分校化学系,访问学者

  • 工作经历

    2004-2006:中国赌博十大网站,博士后
    2007-2011:中国赌博十大网站,讲师
    2012至今:中国赌博十大网站,副研究员

  • 研究方向

    1、金属有机催化的合成方法学研究。
    2、药物、及其中间体合成工艺的优化。

  • 科研项目

    主持和参加国家自然科学基金、国家重点实验室开放基金以及与国内、外企业合作多项课题研究。

  • 代表性论文专著

    论文 

    1. Xie, X.; Lu, B.; Li, W.; Zhang, Z.*, “Coordination determined chemo- and enantioselectivities in asymmetric hydrogenation of multi-functionalized ketones” Coord. Chem. Rev. 2018, 355, 39-53.
    2. Wu, X.; Ding, G.; Yang, L.; Lu, W.; Li, W.; Zhang, Z.; Xie, X.*, “Alkoxide-catalyzed hydrosilylation of cyclic imides to isoquinolines via tandem reduction and rearrangement”Org. Lett. 2018, 20, 5610-5613.
    3. Ding, G.; Wu, X.; Lu, B.; Lu, W.; Zhang, Z.*; Xie, X.*, “Tri(pentaflurophenyl)borane-catalyzed reduction of cyclic imides with hydrosilanes: Synthesis of pyrrolidines”Tetrahedron. 2018, 74, 1144-1150.
    4. Shen, Y.; Zhou, Y.; Jiang, L.;Ding, G.; Luo, L.; Zhang, Z.; Xie, X.*, “Selective aerobic oxidation of benzylic amines to aryl nitriles catalyzed by CuBr2/N-methyl imidazole”Tetrahedron. 2018, 74, 604-614.
    5. Cai, L.; Huang, Z.; Yang, L.; Xie, X.*; Tao, X.*,“Selective Aerobic Oxidation of Benzylic Alcohols Catalyzed by CuBr/1,8-Diazabicyclo[5.4.0]undec-7-ene”Chin. J. Org. Chem. 2018, 38, 3326-3331. 
    6. Ding, G.; Wu, X.; Jiang, L.; Zhang, Z.*; Xie, X.*, “Reduction of benzolactams to isoindoles via an alkoxide-catalyzed hydrosilylation”Org. Lett. 2017, 19, 6048-6051. 
    7. Tao, X.; Li, L.; Zhou, Y.; Qian, X.; Zhao, M.*; Cai, L.; Xie, X.*,“PdCl2(Ph3P)2/Salicylaldimine Catalyzed Diarylation of Anilines with Unactivated Aryl Chlorides”Chin. J. Chem. 2017, 35, 1749-1754.
    8. Ding, G.; Li, C.; Shen, Y.; Lu, B. Zhang, Z.*; Xie, X.*, “Potassium hydroxide-catalyzed chemoselective reduction of cyclic imides with hydrosilanes: synthesis of ω-hydroxylactams and lactams” Adv. Synth. Catal. 2016, 358, 1241-1251.
    9. Xie, X.; Stahl, S. S.* “Efficient and selective Cu/nitroxyl-catalyzed methods for aerobic oxidative lactonization of diols”J. Am. Chem. Soc. 2015, 137, 3767-3770.
    10. Ding, G.; Lu, B.; Li, Y.; Wan, J.*; Zhang, Z.; Xie, X.* “Zinc-Catalyzed Selective Reduction of Cyclic Imides with Hydrosilanes: Synthesis of ω-hydroxylactams” Adv. Synth. Catal. 2015, 357, 1013-1021.
    11. Zhang, Y.; Ni, G.; Li, C.; Xu, S.; Zhang, Z.*; Xie, X.* “The coupling reactions of aryl halides and phenols catalyzed by palladium and MOP-type ligands” Tetrahedron. 2015, 71, 4927-4932.
    12. Tu, Y.; Zhang, Y.; Xu, S.*; Zhang, Z.; Xie, X.* “Cyanation of Unactivated Aryl Chlorides and Aryl Mesylates Catalyzed by Palladium and Hemilabile MOP-Type Ligands” Synlett. 2014, 25, 2938-2942.
    13. Cai, L.; Qian. X.; Song, W.; Liu, T.; Tao, X.*; Li, W.; Xie, X.* “Effects of solvent and base on the palladium-catalyzed amination: PdCl2(Ph3P)2/Ph3P-catalyzed selective arylation of primary anilines with aryl bromides” Tetrahedron. 2014, 70, 4754-4759. 
    14. Xie, X.*; Ni, G.; Ma, F.; Ding, L.; Xu, S.; Zhang, Z. “Palladium-catalyzed monoarylation of aryl amine with aryl tosylates.” Synlett. 2011, 955-958.
    15. Ma, F.; Xie, X.*; Ding, L.; Gao, J.; Zhang, Z.* “Palladium-catalyzed coupling reaction of amino acids (esters) with aryl bromides and chlorides. ” Tetrahedron. 2011, 67, 94055-9410.
    16. Xie, X.*; Ding, L.; Ni, G.; Zhang, Z. Gao, J. “A general and facile approach for the synthesis of 2’-functionalized 1,1’- binapthyl-2-ols.” Chin. J. Chem. 2010, 28, 1630-1634.
    17. Xie, X.; Zhang T.; Zhang, Z.* “Synthesis of bulky and electron-rich MOP-type ligands and their applications in palladium-catalyzed C-N bond formation.” J. Org. Chem. 2006, 71, 6522-6529.

  • 教学工作

    本科生:有机化学、有机化学实验、有机化学综合实验

地址:上海市东川路800号 200240
电话:021-54742893
E-mail:sjtuscce@sjtu.edu.cn

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